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Journal: Journal of Inflammation Research
Article Title: Advancing Polyphenol-Based Nanomedicine for Inflammatory Bowel Disease: Challenges and Opportunities
doi: 10.2147/JIR.S487942
Figure Lengend Snippet: TA-armored nanoparticles and probiotic delivery systems. ( a ) Synthesis scheme for siRNA-GBSA(CHI/TA) n NPs. Reproduced from He H, Qin Q, Xu F, et al. Oral polyphenol-armored nanomedicine for targeted modulation of gut microbiota–brain interactions in colitis. Sci Adv . 2023;9(21):eadf3887. Creative Commons. ( b ) The nanoarmor facilitates rapid and highly biocompatible encapsulation of individual cells, protecting against a diverse range of antibiotics with varying molecular structures and properties. Reproduced with permission from ref. ( c ) Diagram illustrates the SGM preparation process. Reprinted from Chem Eng J . Volume 446. Yang J, Zhang G, Yang X, et al. An oral “Super probiotics” with versatile self-assembly adventitia for enhanced intestinal colonization by autonomous regulating the pathological microenvironment. 137204, Copyright 2022, with permission from Elsevier. ( d ) The therapeutic bacteria are decorated with TA and mucin using layer-by-layer coating technology. Reproduced from Yang X, Yang J, Ye Z, et al. Physiologically inspired mucin coated Escherichia coli nissle 1917 enhances biotherapy by regulating the pathological microenvironment to improve intestinal colonization. ACS Nano . 2022;16(3):4041–4058. Copyright 2022. American Chemical Society.
Article Snippet: Figure 3 TA-armored nanoparticles and
Techniques: Encapsulation, Probiotics, Bacteria